منابع مشابه
Translational neuroscience approaches to hyperphagia.
Introduction 1Food intake in humans and other mammals is a complex process, resulting from the integration of homeostatic systems that monitor energy stores with hedonic drive resulting from the behaviorally reinforcing properties of food (Fig. 1) (Lutter and Nestler, 2009). Under conditions of food scarcity, the hedonic and homeostatic drives cooperate to enhance the intake of highly palatable...
متن کاملFood reward, hyperphagia, and obesity.
Given the unabated obesity problem, there is increasing appreciation of expressions like "my eyes are bigger than my stomach," and recent studies in rodents and humans suggest that dysregulated brain reward pathways may be contributing not only to drug addiction but also to increased intake of palatable foods and ultimately obesity. After describing recent progress in revealing the neural pathw...
متن کاملFood Intake and Hypothalamic Hyperphagia †
Animals eat different amounts of different diets, which implies that they recognize some quality or qualities of the diet. Both Cowgill' and Adolph1 were aware of this problem, but no one appears to have made a systematic attempt to define the dietary quality recognized by animals. Both of these workers were led to the opinion that their animals seemed to "eat for calories," i.e., for energy. H...
متن کاملGhrelin causes hyperphagia and obesity in rats.
Ghrelin, a circulating growth hormone-releasing peptide derived from the stomach, stimulates food intake. The lowest systemically effective orexigenic dose of ghrelin was investigated and the resulting plasma ghrelin concentration was compared with that during fasting. The lowest dose of ghrelin that produced a significant stimulation of feeding after intraperitoneal injection was 1 nmol. The p...
متن کاملHyperphagia in neonates withdrawing from methadone.
AIMS To examine whether hyperphagia is a clinically significant problem in infants born to women receiving methadone maintenance. METHODS The volume of feeds, changes in infant body weight, as well as occurrence of adverse clinical effects in infants withdrawing from methadone were studied during the first month of life. A retrospective chart review was conducted for all infants at San Franci...
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ژورنال
عنوان ژورنال: British Journal of Psychiatry
سال: 1999
ISSN: 0007-1250,1472-1465
DOI: 10.1192/s000712500015247x